Restless Legs Syndrome

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Future of RLS

Primary RLS remains a lifelong condition for which there is no cure. Although symptoms may fluctuate during its course, they typically progress over time. Permanent remissions are rare. Current nonpharmacologic measures and prescription medications can generally control symptoms and afford patients some temporary relief. Continued research into the underlying cause of Primary RLS is required to allow investigators to find a permanent cure. According to Dr. John Winkelman, “Despite remarkable advances in the recognition and treatment of restless legs syndrome (RLS) over the past 20 years, there is still a great deal of uncertainty regarding its pathophysiology, etiology, epidemiology, and clinical outcomes. Specific research, including studies yielding better information on the pathophysiology of RLS, is necessary to further define the condition and approaches to treatment.” [22]

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